Technology for obtaining microcapsules to immobilize microorganisms used in biotechnological processes
Title of the offer
Technology for obtaining microcapsules to immobilize microorganisms used in biotechnological processes
Offer description
The subject matter of this proposal is a technology for obtaining microcapsules to immobilize microorganisms used in biotechnological processes. It may be used to immobilize bioactive substances such as microorganism cells, enzymes and active ingredients of drugs, food, feed and fertilizers. The microcapsules are created through the formation of polyelectrolytes and are intended to immobilize hydrophobic compounds and hydrophilic materials of biological origin.
The proposed immobilization method of is one of the methods which consist in immobilizing the material inside the medium. The immobilization process comprises the following stages: preparing an aqueous solution of polyanion; preparing an aqueous solution of polycation; preparing a NaCl solution; sterilization of the aqueous solution of polyanion; introducing the bacterial suspension to the polyanion solution; microencapsulation; complexation of capsule membrane ingredients; sterilization of the NaCl solution; finishing the complexation; adding NaCl; rinsing; process finalization.
Compared to traditional processed based on free cells, the use of immobilized cells provides economic and technological benefits, including: enhancing the activity and stability of the biocatalyst; increasing cell density per unit of volume of the fermenter (resulting in higher productivity); accelerating the fermentation process; eliminating the cell proliferation phase; ability to run continuous processes; reduction of microbiological infections; and reuse of the biocatalyst.
Keywords
Technology for obtaining microcapsules
Scientific field
Industrial biotechnology, Nanotechnology
Industry sector
Feed and rendering industry, Food Industry, Pharmacological industry
Type of technology
Technology
Technology Visualization
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Authors/inventors
prof. dr hab. Włodzimierz Grajekprof. dr hab. Tomasz Jankowski
Rights holder
Poznań University of Life SciencesWest Pomeranian University of TechnologyPoznan University of TechnologyWroclaw University of Life SciencesLublin University of Life Sciences
Poznań University of Life Sciences
Intellectual property rights
National patent
Application number
P. 370183
Patent number
PL. 196926
TRL level
5
Form of transfer
Exclusive license, Non-exclusive license, Rights sale
